Products for Research Use Only
RegisterLogin

EOS (d18:1/32:1/18:2)

CAT: 0931-T37461Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T37461Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1318771-31-1
Target
Others
Related Pathways
Others
Bioactivity
EOS is a ceramide found in the outer layer of the epidermis in mammals. It is comprised of an ω-hydroxy very long-chain ceramide (C28-36) esterified to the essential fatty acid linoleic acid . The consecutive regio- and stereospecific oxygenation of the linoleate portion of EOS by 12 (R) -lipoxygenase (12 (R) -LO) and eLOX3 is essential for the maintenance of the epidermal barrier to prevent water loss. Following oxygenation, the oxidized linoleate is hydrolyzed, leaving the ω-hydroxy end of the very long-chain fatty acid to covalently bind the protein layer, forming the corneocyte lipid envelope and sealing the gap between the extracellular lipid lamellae and the cornified cell envelope of the corneocyte.
Smiles
CCCCCCCCCCCCC\C=C\[C@@H](O)[C@H](CO)NC(=O)CCCCCCCCCCCCCCCCCCCC\C=C/CCCCCCCCCOC(=O)CCCCCCC\C=C/C\C=C/CCCCC
Molecular Formula
C68H127NO5
Molecular Weight
1038.766
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T85165-01EOS (d18:1/30:0/18:2)
T206151-01GlcCer (d18:1/18:0)
TYD-03906-01CER1 (d18:1/28:0/18:2)
TYD-04005-01C18:2 Glucosyl (ß) ceramide (d18:1/18:2)
T85275-01C32 Ceramide (d18:1/32:0)
TYD-04132-011-O-Acyl ceramide (d18:1/18:1/18:1)
T37439C18 Globotriaosylceramide (d18:1/18:0)
T85186-01C18 Sphingomyelin (d18:1/18:0)
T85289-01C18 ((±) -2'-hydroxy) Ceramide (d18:1/18:0)
T35808-01C18:1 Ceramide (d18:1/18:1 (9Z) )

Alternative Products

CatalogName
GTR19190601EOS (d18:1/32:1/18:2)
HY-152022SEOS (d18:1/32:0/18:2) -d9
MBS3920082-01EOS-d9 (d18:1-d9/32:0/18:2)
AR-F09764-0118:1 SM (d18:1/18:1)
AR-F09765-0118:1 SM (d18:1/18:1) -d9
GTR19258737-01GlcCer (d18:1/18:0)
GTR19268488-011-O-Acyl ceramide (d18:1/18:1/18:1)
HY-165066EOS (d18:1/30:0/18:2)
GTR19268242-01CER1 (d18:1/28:0/18:2)
GTR19232162C32 Ceramide (d18:1/32:0)

Popular Products