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13 (S) -HpODE

CAT: 0931-T37393-01Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0931-T37393-01Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
33964-75-9
Target
Endogenous Metabolite, p53, MAO, EGFR
Related Pathways
Tyrosine Kinase/Adaptors, Apoptosis, Angiogenesis, Metabolism, JAK/STAT signaling, Neuroscience
Bioactivity
13 (S) -HpODE, a metabolite present in potato and Homo sapiens, is the (S) -enantiomer of 13-HpODE, a fatty acid containing a peroxy group, IL-13/13 (S) HpODE stimulates MAO-A-mediated intracellular ROS generation and induction of p53 as well as p21 during apoptosis of A549 cancer cells and promotes apoptosis of HCT116 and CCF52 cells by upregulating p53 and p21 expression promoted apoptosis in HCT116 and CCF52 cells, constituting the IL-13 > 15-LO > 13 (S) HpODE > PPARγ > MAO-A > ROS > p53 > p21 axis.
Smiles
[C@@H](/C=C/C=C\CCCCCCCC(O)=O)(CCCCC)OO
Molecular Formula
C18H32O4
Molecular Weight
312.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C