Products for Research Use Only
RegisterLogin

BLX3887

CAT: 0931-T37273-01Size: 500 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T37273-01Size:500 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
934758-70-0
Target
Others, Lipoxygenase
Related Pathways
Others, Metabolism
Bioactivity
BLX3887 is an inhibitor of 15-lipoxygenase type 1 (15-LO-1; IC50 = 32 nM in a cell-free enzyme assay) .1 It is selective for 15-LO-1 over 15-LO-2, which it does not inhibit, 5-LO (IC50 = 472 nM), and 12-LO (IC50 = 3,310 nM) . BLX3887 inhibits the production of 15-LO metabolites selectively in eosinophils over neutrophils when used at a concentration of 10 μM. It also inhibits endocytosis in, and the migration of, isolated human peripheral blood mononuclear cell-derived dendritic cells in vitro.
Smiles
Fc1ccc(NC(=O)c2n[nH]c(Cl)c2Cl)c(Cl)c1
Molecular Formula
C10H5Cl3FN3O
Molecular Weight
308.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
MBS5798213BLX3887

Popular Products