Products for Research Use Only
RegisterLogin

8-hydroxy Efavirenz

CAT: 0931-T37162Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T37162Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
205754-33-2
Target
Others, Apoptosis, JNK
Related Pathways
Apoptosis, Others, MAPK
Bioactivity
8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz . 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B6. It induces apoptosis in rat primary hippocampal neurons and loss of dendritic spines in rat primary hippocampal neuronal cultures when used at a concentration of 0.01 μM.
Smiles
Oc1cc(Cl)cc2c1NC(=O)O[C@]2(C#CC1CC1)C(F)(F)F
Molecular Formula
C14H9ClF3NO3
Molecular Weight
331.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T2393-01Efavirenz
T34250-01Rac-Efavirenz
T25363-01Efavirenz, (R) -
T371618-hydroxy Amoxapine
T74995-018′-Hydroxy ABA
T37163-018-hydroxy Loxapine
T201052-018 Hydroxy PIPAT oxalate
T22535-018-Hydroxy-PIPAT oxalate
T22534-018-Hydroxy-DPAT hydrobromide
T203451-018β-Hydroxy-exo-THC

Alternative Products

CatalogName
CS-O-109288-Hydroxy Efavirenz
H9044-30Rac 8-Hydroxy Efavirenz
TRC-H941815-100MGent-8-Hydroxy Efavirenz
GTR19253497-01(Rac) -8-Hydroxy-efavirenz
440145-018-Hydroxy Efavirenz (~90%)
TRC-H942950-100MG8-Hydroxy Efavirenz 8-O-Sulfate
sc-2106668- (tert-Butyldimethylsilyloxy) 8-Hydroxy Efavirenz
H9044-30FRac 8-Hydroxy Efavirenz-d4

Popular Products