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Luxeptinib

CAT: 0931-T37085-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T37085-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1616428-23-9
Target
BTK, Others, Apoptosis, FLT
Related Pathways
Tyrosine Kinase/Adaptors, Apoptosis, Others, Angiogenesis
Bioactivity
Luxeptinib (CG-806) is a novel pan-FLT3/pan-BTK inhibitor that is administered orally. It exhibits potent and reversible inhibition of these enzymes, acting through a non-covalent mechanism. Luxeptinib effectively induces cell cycle arrest, apoptosis, or autophagy in acute myeloid leukemia cells [1][2][3][4].
Smiles
Cc1c[nH]c(n1)-c1ccc(c2CNC(=O)c12)-c1ccc(NC(=O)Nc2c(F)cc(F)cc2F)cc1F
Molecular Formula
C25H17F4N5O2
Molecular Weight
495.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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