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Naphthofluorescein

CAT: 0931-T36953Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T36953Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
61419-02-1
Target
HIF/HIF Prolyl-Hydroxylase, HIF
Related Pathways
Angiogenesis, Chromatin/Epigenetic, Metabolism
Purity
0.9934
Bioactivity
Naphthofluorescein (Naphthafluorescein) is a Mint3 inhibitor with potential antitumor and anti-inflammatory activities, inhibits the interaction between HIF-1 and Mint3, inhibits Mint3-dependent HIF-1 activity, and inhibits glycolytic activity in cancer cells and macrophages without showing significant in vitro cytotoxicity or in vivo side effects. Naphthofluorescein is also a fluorescent pH-sensitive probe for functional Cherenkov imaging.
Smiles
Oc1ccc2c3Oc4c(ccc5cc(O)ccc45)C4(OC(=O)c5ccccc45)c3ccc2c1
Molecular Formula
C28H16O5
Molecular Weight
432.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

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OR1025378-01Naphthofluorescein
sc-222038Naphthofluorescein di- (β-D-galactopyranoside)
294299-01Naphthofluorescein di-O- (b-D-galactopyranoside)

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