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Pestalotin

CAT: 0931-T36886Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T36886Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
34565-32-7
Target
Others, Endogenous Metabolite
Related Pathways
Metabolism, Others
Bioactivity
Pestalotin is a fungal metabolite originally isolated from P. cryptomeriaecola with diverse biological activities. It induces reducing sugar release in embryoless rice endosperms when used at concentrations ranging from 3 to 100 mg/L and enhances growth of rice seedlings (O. sativa) when used in combination with gibberellin A3 at concentrations ranging from 30 to 500 mg/L. Pestalotin has antifungal activity, reducing the growth of C. albicans, C. neoformans, T. rubrum, and A. fumigatus (MICs = 12.5, 50, 50, and 50 μg/ml, respectively) . It is cytotoxic to HL-60, MKN45, LoVo, and A549 cells (IC50s = 64.87-182.92 μM) . Pestalotin has been used as a standard for dereplication of natural products.
Smiles
[C@@H](CCCC)(O)[C@@]1(CC(OC)=CC(=O)O1)[H]
Molecular Formula
C11H18O4
Molecular Weight
214.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
sc-202278Pestalotin
P3356-80Pestalotin (6-Hydroxy-3-methoxy-2-decen-5-olide, Antibiotic LL-P880 alpha)

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