Sclerotiorin

CAT: 0931-T36878-01Size: 500 µgDry Ice: NoHazardous: No

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CAT#:0931-T36878-01Size:500 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

549-23-5

Target

Others, Lipoxygenase, Antifungal

Related Pathways

Metabolism, Microbiology/Virology, Others

Bioactivity

Sclerotiorin is a natural product isolated primarily from Penicillium species. It inhibits soybean lipoxygenase-1 with an IC50 value of 4.2 μM. Sclerotiorin also exhibits a number of other activities including inhibition of cholesterol ester transfer protein (IC50 = 19.4 μM), , inhibition of Grb2-Shc interaction (IC50 = 22 μM), , and antagonism of endothelin receptors (IC50 = 114 and 152 μM for human ETA and ETB, respectively) .

Smiles

O=C1C=2C(=C(Cl)C(=O)[C@@]1(OC(C)=O)C)C=C(/C=C/C(=C/[C@H](CC)C)/C)OC2

Molecular Formula

C21H23ClO5

Molecular Weight

390.86

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Alternative Products

Catalog	Name
2334-1000	Sclerotiorin
MBS6059674-01	Sclerotiorin ((S-(R,R-(E,E)))-Sclerotiorin)
465957-01	Sclerotiorin ((S- (R, R- (E, E) ) ) -Sclerotiorin) discontinued. See 045275

Sclerotiorin

Alternative Products

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