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Chevalone C

CAT: 0931-T36815-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T36815-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1318025-77-2
Target
Parasite, Others
Related Pathways
Microbiology/Virology, Others
Bioactivity
Chevalone C is a meroterpenoid fungal metabolite originally isolated from E. chevalieri. It is active against M. tuberculosis H37Ra (MIC = 6.3 μg/ml) and is cytotoxic to BC1 human breast cancer cells (IC50 = 8.7 μg/ml) . Chevalone C inhibits the growth of multidrug-resistant isolates of E. coli, S. aureus, and E. faecium in a disc diffusion assay when used at a concentration of 15 μg/disc. It also induces cell death in HCT116 colorectal carcinoma cells.
Smiles
[H][C@@]12CC[C@]3(C)[C@]([H])(CC[C@]4(C)Oc5oc(C)cc(=O)c5C[C@@]34[H])[C@@]1(C)CC[C@H](OC(C)=O)C2(C)C
Molecular Formula
C28H40O5
Molecular Weight
456.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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