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10-hydroxy Warfarin

CAT: 0931-T36769-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0931-T36769-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
83219-99-2
Target
Others, Drug Metabolite, Cytochromes P450
Related Pathways
Others, Metabolism
Bioactivity
10-hydroxy Warfarin is a metabolite of (R) -warfarin .1It is formed from (R) -warfarin by the cytochrome P450 (CYP) isoform CYP3A4. 10-hydroxy Warfarin is an inhibitor of CYP2C9 (IC50= 1.6 μM), the enzyme that converts (S) -warfarin to its 6-hydroxy warfarin and 7-hydroxy warfarin metabolites.2
Smiles
CC(=O)C(O)C(c1ccccc1)c1c(O)c2ccccc2oc1=O
Molecular Formula
C19H16O5
Molecular Weight
324.332
Shipping Conditions
Ice Packs
Storage Temperature
-20°C