10-hydroxy Warfarin

• Target :

  Others|||Drug Metabolite|||Cytochromes P450

• Related Pathways :

  Others|||Metabolism

• Bioactivity :

  10-hydroxy Warfarin is a metabolite of (R) -warfarin .1It is formed from (R) -warfarin by the cytochrome P450 (CYP) isoform CYP3A4. 10-hydroxy Warfarin is an inhibitor of CYP2C9 (IC50= 1.6 ?M), the enzyme that converts (S) -warfarin to its 6-hydroxy warfarin and 7-hydroxy warfarin metabolites.2

• Smiles :

  CC(=O)C(O)C(c1ccccc1)c1c(O)c2ccccc2oc1=O

• Molecular Formula :

  C19H16O5

• Molecular Weight :

  324.332

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  83219-99-2