10-hydroxy Warfarin

CAT: 0931-T36769-01Size: 500 µgDry Ice: NoHazardous: No
CAT#:0931-T36769-01Size:500 µg
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CAS Number
83219-99-2
Target
Others|||Drug Metabolite|||Cytochromes P450
Related Pathways
Others|||Metabolism
Bioactivity
10-hydroxy Warfarin is a metabolite of (R) -warfarin .1It is formed from (R) -warfarin by the cytochrome P450 (CYP) isoform CYP3A4. 10-hydroxy Warfarin is an inhibitor of CYP2C9 (IC50= 1.6 ?M), the enzyme that converts (S) -warfarin to its 6-hydroxy warfarin and 7-hydroxy warfarin metabolites.2
Smiles
CC(=O)C(O)C(c1ccccc1)c1c(O)c2ccccc2oc1=O
Molecular Formula
C19H16O5
Molecular Weight
324.332
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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