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Sesamol

CAT: 0931-T3676-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T3676-01Size:1 mL - 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
533-31-3
Target
AMPK, Apoptosis
Related Pathways
PI3K/Akt/mTOR signaling, Apoptosis, Chromatin/Epigenetic
Purity
>99.99%
Bioactivity
Sesamol (1,3-Benzodioxol-5-ol) could decrease lung inflammation and lipopolysaccharide (LPS) -induced lung injury in rats. Sesamol ameliorates inflammatory and oxidative damage by upregulating AMPK activation and Nrf2 signaling and blocking the NF-κB and MAPK signaling pathways and inhibits melanin biosynthesis by down-regulating tyrosinase activity and melanin production via regulation of gene expression of melanogenesis-related proteins through modulation of MITF activity, which promotes phosphorylation of p38 and JNK in melan-a cells.
Smiles
OC1=CC2=C(OCO2)C=C1
Molecular Formula
C7H6O3
Molecular Weight
138.12
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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