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Didesmethylrocaglamide

CAT: 0931-T36750-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T36750-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
177262-30-5
Target
Others, PERK, Apoptosis
Related Pathways
Apoptosis, Others
Bioactivity
Didesmethylrocaglamide, a Rocaglamide derivative, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor that exhibits strong growth-inhibitory effects, with an IC50 of 5 nM. It hinders several growth-promoting signaling pathways and triggers apoptosis in tumor cells, demonstrating antitumor activity[1].
Smiles
COc1ccc(cc1)[C@@]12Oc3cc(OC)cc(OC)c3[C@]1(O)[C@H](O)[C@@H]([C@H]2c1ccccc1)C(N)=O
Molecular Formula
C27H27NO7
Molecular Weight
477.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BA2947-5Didesmethylrocaglamide

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