XY028-140

• Target:

  PROTACs|||CDK

• Related Pathways:

  Cell Cycle/Checkpoint|||PROTAC

• Purity:

  0.9859

• Bioactivity:

  XY028-140 is a selective CDK4/CDK6 degrade and inhibits both CDK4/6 expression and activity in cancer cells. XY028-140 is a PROTAC connected by ligands for Cereblon and CDK.

• Smiles:

  O=C1N(C=2C(C(C)=C1C(C)=O)=CN=C(NC3=CC=C(C=N3)N4CCN(C(CNC5=C6C(C(=O)N(C6=O)C7C(=O)NC(=O)CC7)=CC=C5)=O)CC4)N2)C8CCCC8

• Molecular Formula:

  C39H40N10O7

• Molecular Weight:

  760.8

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2229974-83-6