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Rineterkib hydrochloride

CAT: 0931-T36676Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T36676Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1715025-34-5
Target
Raf, Ras, ERK, Kras, Others
Related Pathways
Others, MAPK
Bioactivity
Rineterkib hydrochloride (compound B) is an orally active RAF and ERK1/2 inhibitor used in treating proliferative diseases characterized by activating mutations in the MAPK pathway, particularly KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC), and KRAS-mutant ovarian cancer[1].
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Cl.CNC[C@@H](NC(=O)c1ccc(cc1F)-c1nc(cnc1N)[C@H]1CC[C@H](O)[C@@H](F)C1)c1cc(F)cc(Br)c1
Molecular Formula
C26H28BrClF3N5O2
Molecular Weight
614.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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