Rineterkib hydrochloride

CAT: 0931-T36676Size: 25 mgDry Ice: NoHazardous: No
CAT#: T36676Size: 25 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1715025-34-5
Target
Raf|||Ras|||ERK|||Kras|||Others
Related Pathways
Others|||MAPK
Bioactivity
Rineterkib hydrochloride (compound B) is an orally active RAF and ERK1/2 inhibitor used in treating proliferative diseases characterized by activating mutations in the MAPK pathway, particularly KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC), and KRAS-mutant ovarian cancer[1].
Smiles
Cl.CNC[C@@H](NC(=O)c1ccc(cc1F)-c1nc(cnc1N)[C@H]1CC[C@H](O)[C@@H](F)C1)c1cc(F)cc(Br)c1
Molecular Formula
C26H28BrClF3N5O2
Molecular Weight
614.89
Shipping Conditions
Cool pack
Storage Temperature
-20°C