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ZQ-16

CAT: 0931-T36634-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T36634-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
376616-73-8
Target
GPCR
Related Pathways
GPCR/G Protein, Endocrinology/Hormones
Purity
0.9852
Bioactivity
ZQ-16 is a potent and highly selective agonist for the G protein-coupled receptor GPR84, demonstrating a half-maximal effective concentration (EC50) of 0.213 μM, and it activates multiple downstream signaling pathways including calcium mobilization, inhibition of cAMP accumulation, phosphorylation of extracellular signal-regulated protein kinase 1/2 (ERK1/2), receptor desensitization and internalization, and receptor-β-arrestin interaction, making it a useful tool compound for studying GPR84 function and a candidate for further optimization.
Smiles
O=C1C=C(O)N=C(SCCCCCC)N1
Molecular Formula
C10H16N2O2S
Molecular Weight
228.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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