(±) 5-iPF2α-VI

• Target :

  Others|||Prostaglandin Receptor

• Related Pathways :

  Immunology/Inflammation|||Others|||GPCR/G Protein

• Bioactivity :

  Isoprostanes are prostaglandin (PG) -like products of free-radical induced lipid peroxidation. Although the isoprostanes derived from arachidonic acid are the best characterized, many other polyunsaturated fatty acids can form isoprostanes. (±) 5-iPF2?-VI is one of dozens of possible stereo- and regioisomeric isoprostanes which can be formed from arachidonic acid. To date, the most extensively studied of these is 8-isoprostane (8-epi-PGF2?, iPF2?-III) . However, 8-isoprostane is a minor isoprostane constituent when compared to some of the other isomers which form in natural conditions of oxidative stress. (±) 5-iPF2?-VI is an isoprostane from the unique Type VI class of isoprostanes. This class has been shown to be one of the major isoprostane products, in contrast to 8-isoprostane. In addition to being produced in greater abundance than 8-isoprostane, Type VI isoprostanes form internal lactones, which facilitates their extraction and purification from biological samples.

• Smiles :

  CCCCC\C=C/C[C@H]1[C@H](O)C[C@H](O)[C@H]1\C=C\C(O)CCCC(O)=O

• Molecular Formula :

  C20H34O5

• Molecular Weight :

  354.487

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  179094-11-2