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Isodeoxycholic Acid

CAT: 0931-T36585-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T36585-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
566-17-6
Target
Chloride channel, Endogenous Metabolite, Antibacterial
Related Pathways
Microbiology/Virology, Metabolism, Membrane transporter/Ion channel
Purity
0.9812
Bioactivity
Isodeoxycholic Acid is a bile acid that is formed via epimerization of deoxycholic acid by intestinal bacteria. It has a greater critical micelle concentration than DCA, indicating reduced detergent activity, and is less active than DCA in inhibiting growth in a panel of seven gut commensal bacteria species. Isodeoxycholic Acid (0.1%) inhibits spore germination induced by taurocholic acid in several C. difficile strains, as well as decreases the cytotoxicity of C. difficile culture supernatants to Vero cells. Plasma levels of isodeoxycholic acid are decreased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet.
Smiles
C[C@@]12[C@@]3([C@]([C@]4([C@](C)([C@@H](O)C3)[C@@]([C@@H](CCC(O)=O)C)(CC4)[H])[H])([C@H](O)C[C@@]1(CCCC2)[H])[H])[H]
Molecular Formula
C24H40O4
Molecular Weight
392.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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