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Nornidulin

CAT: 0931-T36541-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T36541-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
33403-37-1
Target
Others, Antibacterial
Related Pathways
Microbiology/Virology, Others
Bioactivity
Nornidulin is a depsidone originally isolated from [A. nidulans] with antibacterial activity against [M. tuberculosis] and [M. ranoe], and antifungal activity against [T. tonsurans] and [M. audouini]. It inhibits the growth of methicillin-resistant [S. aureus] (MRSA; MIC = 2 μg/ml) and has larvicidal activity toward Artemia (LC50 = 1.7 μg/ml) . Nornidulin exhibits cytotoxic activity in MOLT-3 cells (IC50 = 35.7 μM) but not in HuCCA-1, HepG2, or A549 cells (IC50s = >116.4 μM) .
Smiles
C\C=C(/C)c1c(Cl)c(O)c(C)c2OC(=O)c3c(C)c(Cl)c(O)c(Cl)c3Oc12
Molecular Formula
C19H15Cl3O5
Molecular Weight
429.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C