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Extracellular Death Factor

CAT: 0931-T36523Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T36523Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
960129-66-2
Target
Antibacterial
Related Pathways
Microbiology/Virology
Bioactivity
Programmed cell death in bacteria is dependent on a system of cell-to-cell communication termed quorum sensing. Extracellular death factor (EDF) is a linear pentapeptide that communicating cells produce and release, which upon reaching a sufficient concentration activates the cell death pathway in a subset of cells. It is sensitive to extreme pH, high temperatures, and other stressful conditions. At 2.5 ng/ml, EDF has been shown to facilitate mazEF-mediated cell death, significantly reducing population size in E. coli cultures.
Smiles
N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O
Molecular Formula
C27H36N10O10
Molecular Weight
660.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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