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Gramicidin A

CAT: 0931-T36439-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T36439-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
11029-61-1
Target
HIF/HIF Prolyl-Hydroxylase, Parasite, Antibiotic, HIF, Antibacterial
Related Pathways
Microbiology/Virology, Angiogenesis, Metabolism, Chromatin/Epigenetic
Bioactivity
Gramicidin A is a peptide antibiotic isolated from B. brevis.Gramicidin A is a highly hydrophobic channel-forming ion carrier that forms monovalent cation-permeable channels in artificial membranes.Gramicidin A induces the degradation of hypoxia-inducible factor 1 alpha (HIF-1 alpha) and reduces the growth of a mouse xenograft model of human renal cell carcinoma. Gramicidin A has antibacterial, antimalarial and hemolytic activities.
Smiles
CC(C)CC(NC(=O)C(C)NC(=O)CNC(=O)C(NC=O)C(C)C)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCO
Molecular Formula
C99H140N20O17
Molecular Weight
1882.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
G038-5GGramicidin
MBS3847560-01Gramicidin A

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