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Diminutol

CAT: 0931-T36358-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0931-T36358-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
361431-33-6
Target
Others, Microtubule Associated
Related Pathways
Cytoskeletal Signaling, Others
Bioactivity
Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin polymerization.
Smiles
S(C1=C2C(N(C(C)C)C=N2)=NC(N[C@H](C(C)C)CO)=N1)C3=CC(N)=CC=C3
Molecular Formula
C19H26N6OS
Molecular Weight
386.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19191478-01Diminutol

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