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Psammaplin A

CAT: 0931-T36303Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T36303Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
110659-91-1
Target
Antibacterial, HDAC, DNA Methyltransferase, DNA/RNA Synthesis, Others
Related Pathways
Cell Cycle/Checkpoint, Microbiology/Virology, DNA Damage/DNA Repair, Chromatin/Epigenetic, Others
Bioactivity
Psammaplin A, a marine metabolite, functions as a robust inhibitor of HDAC and DNA methyltransferases, displaying notable potency and selectivity as a DAC1 inhibitor, with an IC50 value of 0.9 nM. It exhibits antimicrobial effects against Gram-positive bacteria and inhibits DNA synthesis and DNA gyrase activity, demonstrating antitumor activity [1][2].
Smiles
O\N=C(/Cc1ccc(O)c(Br)c1)C(=O)NCCSSCCNC(=O)C(\Cc1ccc(O)c(Br)c1)=N\O
Molecular Formula
C22H24Br2N4O6S2
Molecular Weight
664.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
sc-258049Psammaplin A
A24361-10Psammaplin A 10mg
A24361-5Psammaplin A 5mg
A24361-50Psammaplin A 50mg
A24361-1Psammaplin A 1mg
207357-01Psammaplin A discontinued. See 463162

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