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Methylspinazarin

CAT: 0931-T36207Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T36207Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
41768-12-1
Target
Others, Transferase
Related Pathways
Others, Metabolism
Bioactivity
Methylspinazarin is a naphthoquinone bacterial metabolite that has been found in Streptomyces and is an inhibitor of catechol O-methyltransferase (COMT; IC50 = 0.8 μg/ml) .1 It is selective for COMT over tyrosine hydroxylase, DOPA decarboxylase, and dopamine-β-hydroxylase at 100 μg/ml. Methylspinazarin decreases blood pressure in spontaneously hypertensive rats when administered at a dose of 50 mg/kg.
Smiles
Cc1cc(O)c2C(=O)C(O)=C(O)C(=O)c2c1O
Molecular Formula
C11H8O6
Molecular Weight
236.18
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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