Methylatropine (nitrate)

• Target:

  Others|||AChR

• Related Pathways:

  Others|||Neuroscience

• Bioactivity:

  Methylatropine is an antagonist of muscarinic acetylcholine receptors (IC50= <0.1 nM in a radioligand binding assay using isolated porcine brain membranes) and a derivative of atropine .1,2It reduces acetylcholine-induced decreases in blood pressure in rats when administered intravenously with an ED50value of 5.5 ?g/kg.2Methylatropine reduces salivation, induces mydriasis, and increases heart rate in dogs.3

• Smiles:

  [O-]N(=O)=O.[H][C@]12CC[C@]([H])(C[C@@H](C1)OC(=O)C(CO)c1ccccc1)[N+]2(C)C|TLB:13:11:25:6.7|

• Molecular Formula:

  C18H26N2O6

• Molecular Weight:

  366.414

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  52-88-0