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14,15-EE-5 (Z) -E

CAT: 0931-T36150-01Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0931-T36150-01Size:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
519038-92-7
Target
Others, Endogenous Metabolite
Related Pathways
Others, Metabolism
Bioactivity
Epoxyeicosatrienoic acids (EETs), such as 11 (12) -EET and 14 (15) -EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity. 14,15-EE-5 (Z) -E is a structural analog of 14,15-epoxyeicosatrienoic acids (14,15-EET) that antagonizes EET-induced relaxation of vascular smooth muscle. Relaxation of U46619-constricted bovine arteries by 14,15-EET could be inhibited approximately 80% by 14,15-EE-5 (Z) -E at a concentration of 10 μM. 14,15-EE-5 (Z) -E does not appear to antagonize nitric oxide- or iloprost-mediated vascular relaxation.
Smiles
CCCCC[C@@H]1O[C@@H]1CCCCCCC\C=C/CCCC(O)=O
Molecular Formula
C20H36O3
Molecular Weight
324.505
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

CatalogName
HY-120954-0114,15-EE-5 (Z) -E
MBS579734614,15-EE-5(Z)-E
sc-20501114,15-EE- (5Z) -E
HY-16506714,15-EE-8 (Z) -E
MBS579734714,15-EE-8(Z)-E
sc-2211568,9-EE-14 (Z) -E
GTR19222563-01(±) 8 (9) -EE-14 (Z) -E
MBS5797667(+/-)8(9)-EE-14(Z)-E
412022-0114,15-Epoxyeicosatrienoic Acid (±14,15-EET)
HY-175098(±) 14 (15) -DiHETE

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