K-TMZ

CAT: 0931-T36100-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T36100-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
2269482-26-8
Target
Others
Related Pathways
Others
Bioactivity
K-TMZ is a DNA alkylating agent. It increases the concentration of O6-methylated deoxyguanosine in U87 glioblastoma multiforme (GBM) cells in a concentration-dependent manner. K-TMZ reduces cell viability of GBM cell lines lacking (IC50s = 18-44 ?M) or expressing O6-methylguanine DNA methyltransferase (MGMT; IC50s = 115-240 ?M) . K-TMZ can cross the blood-brain barrier and increases survival in a Br23c mouse xenograft model of GBM when administered at a dose of 14.9 mg/kg.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName
T209244-01MMC (TMZ) -TOC
T204151-01MMC (TMZ) -TOC TFA
TN9923-01Sannamycin K
T70156-01K-5a2
T70949-01K-8986
T80980-01Tityustoxin-Kα
T79181-01K-80001
TN7755-01Parishin K
TN7972-01Tenuifoliose K
T32352K 486

Alternative Products

CatalogName
HY-115690K-TMZ
C07644-01TMZ (Temozolomide)
HY-169433Naph-Se-TMZ
HY-163317MMC (TMZ) -TOC
HY-163317A-01MMC (TMZ) -TOC (TFA)
AFG-ELL-0039Human Astroglioma Temozolomide Resistant Cells [U251 MG/TMZ]
AFG-ELL-0040Human Astroglioma Temozolomide Resistant Cells+Luc [U251 MG/TMZ+Luc]
351334-01KRAS (GTPase Kras, C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, NS3, RASK2, GTPase Kras, K-RAS2A, K RAS2B, K RAS4A, K RAS4B, KI RAS, KRAS 1, NS 3)
MBS1070614-01Recombinant Escherichia coli Protein K (K)
RM-Z240000-01S-Antcin K; Zhankuic acid K

Popular Products