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JMV3002

CAT: 0931-T35793-01Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0931-T35793-01Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
925239-03-8
Target
GHSR, Others
Related Pathways
Others, GPCR/G Protein
Bioactivity
JMV3002 is a potent ghrelin receptor antagonist with an IC50 value of 1.1 nM in vitro. At 80 μg/kg, JMV3002 inhibits hexarelin-stimulated food intake by up to 98% in rats. It does not induce growth hormone release nor inhibit hexarelin-stimulated growth hormone secretion at a dose of 160 μg/kg in infant rats.
Smiles
C(N1C([C@@H](CC=2C=3C(NC2)=CC=CC3)NC(=O)C4=CC=CC=N4)=NN=C1CCC5=CC=CC=C5)C6=C(OC)C=C(OC)C=C6
Molecular Formula
C35H34N6O3
Molecular Weight
586.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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452860-01JMV3002

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