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Aszonapyrone A

CAT: 0931-T35754Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T35754Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
83103-08-6
Target
Others, Antifungal, Antibacterial
Related Pathways
Microbiology/Virology, Others
Bioactivity
Aszonapyrone A is a meroditerpene fungal metabolite that has been found in Neosartorya and has diverse biological activities.1,2,3 It inhibits the growth of MCF-7, NCI H460, and A375-C5 cancer cells (GI50s = 13.6, 11.6, and 10.2 μM, respectively) .1 Aszonapyrone A is active against multidrug-resistant isolates of S. aureus, E. faecalis, and E. faecium (MICs = 8, 16, and 16 μg/ml, respectively) and inhibits S. aureus biofilm formation.2 It is also active against P. falciparum in vitro (IC50 = 1.34 μg/ml) .3
Smiles
[H][C@@]12CC[C@@]3(C)[C@H](Cc4c(O)cc(C)oc4=O)C(=C)CC[C@]3([H])[C@@]1(C)CC[C@H](OC(C)=O)C2(C)C
Molecular Formula
C28H40O5
Molecular Weight
456.623
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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