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Gliovirin

CAT: 0931-T35741Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T35741Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
83912-90-7
Target
Antifungal, Others, Antibiotic
Related Pathways
Microbiology/Virology, Others
Bioactivity
Gliovirin is a fungal metabolite that has been found inT. harzianumand has fungicidal, antimicrobial and anti-inflammatory activities.1It is active against the plant pathogenic fungusP. ultimum (MIC = 60 ng/ml) and the parasiteT. brucei brucei (IC50= 90 ng/ml), but has no effect on the plant pathogenic fungiR. solani, P. omnivorum, T. basicola, R. arrhizus, andV. dahliaeor the bacteriaB. thuringiensis, P. fluorescens, andX. malvacearumwhen used at concentrations up to 1,000 ng/ml.2,3Gliovirin decreases phorbol 12-myristate 13-acetate (TPA) - and ionomycin-induced increased expression of COX-2 (IC50= 1 μM) and protein levels of IL-2 in Jurkat cells (IC50= 5.2 μM) .1
Smiles
COc1ccc(C2SSC34CC56OC5C=CC(O)C6ON3C(=O)C2NC4=O)c(O)c1OC
Molecular Formula
C20H20N2O8S2
Molecular Weight
480.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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