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PW0787

CAT: 0804-HY-138639-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-138639-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PW0787 is a potent, selective, orally active, and brain-penetrant GPR52 agonist (EC50=135 nM) . PW0787 suppresses psychostimulant behavior[1].
CAS Number
2624131-45-7
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
GPR52
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pw0787.html
Concentration
10mM
Purity
98.79
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CC2=C1CCN2C3=NC=NC(CC4=CC(F)=CC(C(F)(F)F)=C4)=C3)NCCO
Molecular Formula
C23H20F4N4O2
Molecular Weight
460.42
Precautions
H315, H319, H335
References & Citations
[1]Wang P, et al. Discovery of Potent and Brain-Penetrant GPR52 Agonist that Suppresses Psychostimulant Behavior. J Med Chem. 2020;63 (22) :13951-13972.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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