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FR901379

CAT: 0931-T35700-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T35700-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
144371-88-0
Target
Others, Antibiotic
Related Pathways
Microbiology/Virology, Others
Bioactivity
FR901379 is an echinocandin-like antifungal lipopeptide.1 It is active against C. albicans, C. krusei, C. tropicalis, C. utilis, A. fumigatus, and A. niger fungi (IC50s = <0.003-1.9 μg/ml) . FR901379 is protective against C. albicans infection in mice (ED50 = 1.1 mg/kg) . It also reduces the number of pulmonary cysts and trophozoites in a mouse model of P. carinii infection.
Smiles
CCCCCCCCCCCCCCCC(=O)N[C@H]1C[C@@H](O)[C@H](O)NC(=O)[C@@H]2[C@@H](O)[C@@H](C)CN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC1=O)[C@@H](C)O)[C@H](O)[C@@H](O)c1ccc(O)c(OS(O)(=O)=O)c1)[C@H](O)CC(N)=O
Molecular Formula
C51H82N8O21S
Molecular Weight
1175.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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GTR19191926-01FR901379

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