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Myxochelin A

CAT: 0931-T35692Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T35692Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
120243-02-9
Target
Others, Lipoxygenase
Related Pathways
Metabolism, Others
Bioactivity
Myxochelin A is a microbial metabolite found in *A. disciformis* with diverse biological activities. It exhibits activity against Gram-positive bacteria, including *B. cereus*, *S. aureus*, and *M. luteus*, but not against Gram-negative bacteria or fungi at a concentration of 80 μg/disc in an agar diffusion assay. Myxochelin A inhibits 5-lipoxygenase (5-LO) activity, with an IC50 value of 1.9 μM for the recombinant human enzyme. Additionally, it is cytotoxic to 26-L5 colon cancer cells at a concentration of 3 μg/ml.
Smiles
OC[C@H](CCCCNC(=O)c1cccc(O)c1O)NC(=O)c1cccc(O)c1O
Molecular Formula
C20H24N2O7
Molecular Weight
404.419
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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