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2-deoxy-D-Glucose-13C6

CAT: 0931-T35683-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T35683-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
201612-55-7
Target
Others, Apoptosis, Hexokinase, HSV
Related Pathways
Microbiology/Virology, Metabolism, Apoptosis, Others
Bioactivity
2-deoxy-D-Glucose-13C6is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS. 2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis.1,2It inhibits hexokinase, the enzyme that converts glucose to glucose-6-phosphate, as well as phosphoglucose isomerase, the enzyme that converts glucose-6-phosphate to fructose-6-phosphate.32-deoxy-D-Glucose (16 mM) induces apoptosis in SK-BR-3 cells, as well as inhibits the growth of 143B osteosarcoma cells cultured under hypoxic conditions when used at a concentration of 2 mg/ml.4,5
Molecular Formula
C5C (13) H12O5
Molecular Weight
165.15
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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