I-SAP

CAT: 0931-MF-0051056-01Size: 100 µgDry Ice: NoHazardous: No
CAT#:0931-MF-0051056-01Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
133538-58-6
Target
Others|||Prostaglandin Receptor
Related Pathways
Others|||GPCR/G Protein|||Immunology/Inflammation
Bioactivity
I-SAP is a high affinity TP receptor antagonist. At physiologic pH, I-SAP produces platelet shape change, but not aggregation, with an EC50 value of 9.7 nM. I-SAP binds to human platelets with the maximum binding obtained between pH 6.5 and pH 7.4. In washed human platelets, the Kd for I-SAP is 468 pM at pH 7.4 and 490 pM at pH 6.5.
Smiles
C(/C=C\CCCC(O)=O)[C@H]1[C@]2(C(C)(C)[C@](C2)(C[C@@H]1NS(=O)(=O)C3=CC=C(I)C=C3)[H])[H]
Molecular Formula
C22H30INO4S
Molecular Weight
531.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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