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Chiauranib

CAT: 0931-T35570-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T35570-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1256349-48-0
Target
PDGFR, VEGFR, FLT, Aurora Kinase, c-Fms, c-Kit
Related Pathways
Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint, Chromatin/Epigenetic, Angiogenesis
Purity
0.9922
Bioactivity
Chiauranib is a multi-target inhibitor against tumor angiogenesis and exhibits potent anticancer effects. Chiauranib potently inhibits the angiogenesis-related kinases (VEGFR1, VEGFR2, VEGFR3, PDGFRα and c-Kit), mitosis-related kinase Aurora B, and chronic inflammation-related kinase CSF1R, with IC50 values ranging from 1-9 nM.
Smiles
COc1ccc2c(Oc3ccc4c(cccc4c3)C(=O)Nc3ccccc3N)ccnc2c1
Molecular Formula
C27H21N3O3
Molecular Weight
435.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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BA3724-50Chiauranib
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