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(±) -Clopidogrel (hydrochloride)

CAT: 0931-T35431-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T35431-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
130209-90-4
Target
Others, P2Y Receptor
Related Pathways
GPCR/G Protein, Neuroscience, Others
Bioactivity
Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM) . Clopidogrel inhibits ADP-induced platelet aggregation ex vivo and functions as a prodrug whereupon biotransformation to its active metabolite via CYP2C19 in the liver enables its anti-aggregating activity. Marketed under the name Plavix , clopidogrel in combination with aspirin has been shown to be beneficial in the prevention of vascular ischemic events for patients without deficiencies in CYP2C19-related metabolism.
Smiles
Cl.O=C(OC)C(C=1C=CC=CC1Cl)N2CC=3C=CSC3CC2
Molecular Formula
C16H17Cl2NO2S
Molecular Weight
358.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C