β-Muricholic Acid

• Target:

  Endogenous Metabolite|||Others

• Related Pathways:

  Metabolism|||Others

• Bioactivity:

  ?-Muricholic acid (?-MCA) is a murine-specific primary bile acid.[1], [2] Dietary administration of ?-MCA reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet.[3] Dietary administration of ?-MCA also dissolves 100% of gallstones in a gallstone-susceptible mouse model of diet-induced cholesterol gallstones.[4]

• Smiles:

  C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCC(O)=O)C)(CC4)[H])[H])([C@@H](O)[C@@H](O)[C@@]1(C[C@H](O)CC2)[H])[H])[H]

• Molecular Formula:

  C24H40O5

• Molecular Weight:

  408.57

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2393-59-1