Thioacetamide

CAT: 0931-T35367-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
CAT#:0931-T35367-01Size:1 mL - 10 mM (in DMSO)
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
62-55-5
Target
Others
Related Pathways
Others
Purity
0.9977
Bioactivity
Thioacetamide (TAA) is an indirect hepatotoxin commonly used to induce experimental liver injury. It is metabolized by CYP2E1 into reactive metabolites that covalently bind to proteins and lipids, leading to oxidative stress and centrilobular necrosis, hepatocyte death, and M1/M2 macrophage-dominated inflammation. TAA is widely used to establish models of chronic liver fibrosis, hepatic encephalopathy, and liver cancer.
Smiles
CC(S)=N
Molecular Formula
C2H5NS
Molecular Weight
75.13
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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