PCI-27483

• Target:

  Others|||Factor VIIa

• Related Pathways:

  Others|||Metabolism

• Purity:

  0.9992

• Bioactivity:

  PCI-27483 is an activated coagulation factor VIIa inhibitor with antithrombotic effects in a baboon model of arterial thrombosis. It also inhibits the growth of BxPC3 xenografts by 42% and 85% at doses of 60 and 90 mg/kg, respectively.

• Smiles:

  NC(=N)c1ccc2[nH]c(nc2c1)-c1cc(CC(=O)N[C@@H](CC(O)=O)C(O)=O)cc(c1O)-c1cc(ccc1O)S(N)(=O)=O

• Molecular Formula:

  C26H24N6O9S

• Molecular Weight:

  596.57

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  871266-63-6