Products for Research Use Only
RegisterLogin

PQA-18

CAT: 0804-HY-171034-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-171034-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PQA-18 is a unique PAK2 inhibitor (IC50: 10 nM) . PQA-18 has immunosuppressing effects. PQA-18 suppresses IL2, IL4, IL6, and TNFα. PQA-18 inhibits the population of a subset of regulatory T cells and the immunoglobulin (Ig) production against T cell-dependent antigens as well as alleviates dermatitis in mice[1].
CAS Number
1604678-82-1
UNSPSC
12352005
Target
Interleukin Related; PAK; TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pqa-18.html
Purity
99.62
Smiles
O=C(C1=NC2=C(OC/C=C(C)/C)C=CC=C2C(OC/C=C(C)/C)=C1)OC/C=C(C)\C
Molecular Formula
C25H31NO4
Molecular Weight
409.52
References & Citations
[1]Ogura M, et al. Prenylated quinolinecarboxylic acid derivative suppresses immune response through inhibition of PAK2. Biochem Pharmacol. 2016 Apr 1;105:55-65.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-2; IL-4; IL-6; PAK2

Related Products

CatalogName
HY-W011222S1-011-Bromooctadecane-18,18,18-d3
HY-N11142Gb3 (18:1/18:0)
HY-143203-0118:0-18:2 PE
HY-W105737-0118-Methoxy-18-oxooctadecanoic acid
HY-CE0053718-CoA-18-oxo-dinor-LTB4
HY-148978-0118:0,18:1 PS (sodium)
HY-W72530918:0-18:1 PA (sodium)
HY-157618-0118:0-18:1 PG (sodium)
HY-N11142SGb3-d7 (18:1/18:0)
HY-170458-0118:0-18:2 PG (sodium)

Alternative Products

CatalogName
T201360-01PQA-18
TRC-S686499-5MGOctadecanoic-18,18,18-d3 Acid
sc-236934Stearic acid-18,18,18-d3
B6873671-Bromooctadecane-18,18,18-d3
T886456Glyceryl Tri(octadecanoate-18,18,18-d3)
MBS343012-01Cytokeratin-18 (CK-18)
MO-C40094A-01Interleukin-18 (IL-18)
GTR19194971CP-18 F-18
MM-1009-02Cytokeratin 18 (CK 18)
228184Cytokeratin 18 (Keratin 18)

Popular Products