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Icaritin

CAT: 0931-T3398-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T3398-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
118525-40-9
Target
STAT, Autophagy, JAK, Apoptosis
Related Pathways
Stem Cells, Chromatin/Epigenetic, Apoptosis, JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors, Autophagy
Purity
0.9976
Bioactivity
Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity. Icaritin has anticancer activity, can induce S phase arrest and apoptosis, inhibit ENKL cell proliferation. Icaritin has anti-multiple myeloma activity, mainly mediated by inhibiting IL-6/JAK2/STAT3 signaling. Icaritin at low concentration (4 or 8 μMol/L) can promote rat chondrocyte proliferation and inhibit cell apoptosis, while the effect of Icaritin on rat chondrocyte at high concentration was reversed.
Smiles
COc1ccc(cc1)-c1oc2c(CC=C(C)C)c(O)cc(O)c2c(=O)c1O
Molecular Formula
C21H20O6
Molecular Weight
368.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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