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PF-04856264

CAT: 0931-T33943-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T33943-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1235397-05-3
Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9743
Bioactivity
PF-04856264 is a Nav1.7 blocker.Nav1.7 is a chondrocyte modulator and a therapeutic target in osteoarthritis.Inhibition of Nav1.7 modulates intracellular Ca 2+ signaling and chondrocyte secretome, raises the threshold of mechanical pain and inhibits ERK expression, which has analgesic and anti-inflammatory effects.
Smiles
N#CC1=CC(=CC=C1OC=2C=CC=CC2C3=CC=NN3C)S(=O)(=O)NC4=NC=CS4
Molecular Formula
C20H15N5O3S2
Molecular Weight
437.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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