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Panduratin A

CAT: 0931-T33875Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T33875Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
89837-52-5
Target
AMPK, MMP, Apoptosis, PPAR, Virus Protease, Antibacterial
Related Pathways
Microbiology/Virology, Metabolism, PI3K/Akt/mTOR signaling, Chromatin/Epigenetic, Proteases/Proteasome, Apoptosis, DNA Damage/DNA Repair
Bioactivity
Panduratin A is a natural chalcone derivative with inhibitory activity against MMP-9 in human oral epidermoid carcinoma KB cells; inhibitory activity against the NS3 protease of DENV-2 (Ki=25 μM) ; significant cytotoxicity against human androgen-independent prostate cancer cells PC-3 and DU-145; and also able to activate the LKB1-AMPK- PPARα /δ signaling pathway and enhance the oxidative capacity of myocyte mitochondria.
Smiles
C(=O)([C@H]1[C@@H](CC=C(C)[C@H]1CC=C(C)C)C2=CC=CC=C2)C3=C(O)C=C(OC)C=C3O
Molecular Formula
C26H30O4
Molecular Weight
406.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

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XP180835(+) -Panduratin A
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AR-P01138-01(±) -Panduratin A
462013-01(±) -Panduratin A discontinued
TRC-P178750-10MG(±)-Panduratin A (>80%)
TRC-P178752-50MG(±)-Panduratin A-d3
462014(±) -Panduratin A-d3

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