RegisterLogin

NSC 109555

CAT: 0931-T33737-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T33737-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
15427-93-7
Target
Others|||Autophagy|||Chk
Related Pathways
Autophagy|||Others|||Cell Cycle/Checkpoint
Bioactivity
NSC 109555 is a selective, reversible, ATP-competitive Chk2 inhibitor (IC50 = 0.2 ?M) that displays no effect on a range of other kinases including Chk1 (IC50 > 10 ?M) . Inhibits histone H1 phosphorylation (IC50 = 0.24 ?M) and attenuates mitochondrial ATP synthesis. Exhibits antiproliferative activity in a number of leukemias in vivo.
Smiles
CS(O)(=O)=O.CS(O)(=O)=O.C\C(=N/N=C(N)N)c1ccc(NC(=O)Nc2ccc(cc2)C(\C)=N\N=C(N)N)cc1
Molecular Formula
C21H32N10O7S2
Molecular Weight
600.67
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName
T1891-01NSC 405020
T33745NSC 341077
T4632-01NSC 6038
T3572-01NSC 15364
T28214-01NSC-79887
T60558-01NSC 694623
T33740-01NSC 157449
T211295-01NSC 330770
T33747-01NSC 695574
T69042-01NSC-279287

Alternative Products

CatalogName
165662NSC 109555
562110NSC-109555 Ditosylate
B7248-10NSC 109555 ditosylate
HY-103366NSC 109555 (ditosylate)

Popular Products