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Levomefolate magnesium

CAT: 0931-T32705-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T32705-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1429498-11-2
Target
Others, Endogenous Metabolite, DNA/RNA Synthesis, ROS
Related Pathways
Metabolism, Immunology/Inflammation, Others, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Bioactivity
Levomefolate magnesium is the magnesium salt of the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma. It is transported across the membranes including the blood-brain barrier into various tissues where it plays an essential role in the DNA synthesis, cysteine cycle and regulation of homocysteine, where it methylates homocysteine and forms methionine and tetrahydrofolate (THF) . Levomefolate is approved as a food additive and is designated a GRAS (generally regarded as safe) compound. It is available commercially as a crystalline form of the calcium salt (Metafolin (R) ), which has the stability required for use as a supplement. Supplementation of levomefolic acid is desired over folic acid due to reduced potential for masking vitamin B12 deficiency symptoms.
Smiles
CN1[C@H](CNc([nH]c(N)n2)c1c2=O)CNc3ccc(C(N[C@H](C([O-])=O)CCC([O-])=O)=O)cc3.[Mg+2]
Molecular Formula
C20H23MgN7O6
Molecular Weight
481.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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