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Ladarixin

CAT: 0931-T32533-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T32533-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
849776-05-2
Target
Akt, NF-κB, CXCR
Related Pathways
Cytoskeletal Signaling, NF-κB, PI3K/Akt/mTOR signaling, GPCR/G Protein, Autophagy, Immunology/Inflammation
Purity
0.9936
Bioactivity
Ladarixin (DF 2156A free base) is an orally active, non-competitive CXCR1/CXCR2 allosteric inhibitor that suppresses AKT, NF-κB, and angiogenesis, thereby slowing the progression of experimental human melanoma. It may be employed in research concerning COPD, asthma, and melanoma.
Smiles
C[C@@H](C(=O)NS(C)(=O)=O)c1ccc(OS(=O)(=O)C(F)(F)F)cc1
Molecular Formula
C11H12F3NO6S2
Molecular Weight
375.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C