Products for Research Use Only
RegisterLogin

Epothilone F

CAT: 0931-T31657-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T31657-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
208518-52-9
Target
Others, Microtubule Associated
Related Pathways
Cytoskeletal Signaling, Others
Bioactivity
Epothilone F is a derivative or analogue of Epothilone D. Epothilone F is also an active metabolite of Epothilone D. In molecule of Epothilone F, a hydroxymethyl group is on the thiazole ring. Like taxanes, Epothilone F prevents cancer cells from dividing by interfering with tubulin. Early studies in cancer cell lines and in human cancer patients indicate superior efficacy to the taxanes. Epothilone's mechanism of action is similar to taxanes, but their chemical structure is simpler. Due to its better water solubility, cremophors (solubilizing agents used for paclitaxel which can affect cardiac function and cause severe hypersensitivity) are not needed.
Smiles
C[C@@]12[C@@](O1)(C[C@@H](\C(=C\C=3N=C(CO)SC3)\C)OC(=O)C[C@H](O)C(C)(C)C(=O)[C@H](C)[C@@H](O)[C@@H](C)CCC2)[H]
Molecular Formula
C27H41NO7S
Molecular Weight
523.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T6490-01Epothilone A
T72934-01Epothilone E
TN8938-01Epothilone C
T82453-01Epothilone D1
TQ0202-01Epothilone D
T6075-01Epothilone B
TN4149Glyasperin F
TN4500-01Marsdenoside F
TN5315Periplocoside F
T124883-01Pseudolarolide F

Alternative Products

CatalogName
A1623-200Epothilone A

Popular Products