CP 461

• Target :

  PDE|||Microtubule Associated|||Apoptosis

• Related Pathways :

  Metabolism|||Cytoskeletal Signaling|||Apoptosis

• Purity :

  0.9982

• Bioactivity :

  CP 461 (UNII-68OJX9I7DT), a specific PDE2A inhibitor, is a novel pro-apoptotic compound that inhibits cyclic GMP phosphodiesterase but not cyclooxygenase-1 or -2. CP 461 inhibits the growth of a variety of human tumor cell lines in vitro and selectively induces apoptosis in cancer cell lines, but not in normal cells.

• Smiles :

  C(C(NCC1=CC=CC=C1)=O)C=2C=3C(/C(=C\C=4C=CN=CC4)/C2C)=CC=C(F)C3.Cl

• Molecular Formula :

  C25H22ClFN2O

• Molecular Weight :

  420.91

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  227619-96-7