Products for Research Use Only
RegisterLogin

AT9283

CAT: 0931-T3068-02Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T3068-02Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
896466-04-9
Target
FLT, Apoptosis, Autophagy, JAK, Aurora Kinase, Bcr-Abl
Related Pathways
Tyrosine Kinase/Adaptors, JAK/STAT signaling, Autophagy, Cell Cycle/Checkpoint, Cytoskeletal Signaling, Stem Cells, Angiogenesis, Chromatin/Epigenetic, Apoptosis
Purity
0.9998
Bioactivity
AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2 (IC50=1.2 nM) and JAK3 (IC50=1.1 nM), Aurora A, Aurora B and Abl (T315I) .
Smiles
O=C(NC1CC1)Nc1c[nH]nc1-c1nc2cc(CN3CCOCC3)ccc2[nH]1
Molecular Formula
C19H23N7O2
Molecular Weight
381.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

At-9283

1-cyclopropyl-3-[3-[5-(4-morpholinylmethyl)-2-benzimidazolylidene]-1,2-dihydropyrazol-4-yl]urea is a member of benzimidazoles.

CAS Number896466-04-9
PubChem CID135398495
IUPAC Name1-cyclopropyl-3-[5-[6-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]urea
Molecular FormulaC19H23N7O2
Molecular Weight381.4
XLogP0.5
Topological Polar Surface Area111
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Heavy Atom Count28
Formal Charge0
Complexity554
SMILES
C1CC1NC(=O)NC2=C(NN=C2)C3=NC4=C(N3)C=C(C=C4)CN5CCOCC5
InChI
InChI=1S/C19H23N7O2/c27-19(21-13-2-3-13)24-16-10-20-25-17(16)18-22-14-4-1-12(9-15(14)23-18)11-26-5-7-28-8-6-26/h1,4,9-10,13H,2-3,5-8,11H2,(H,20,25)(H,22,23)(H2,21,24,27)
InChIKey
LOLPPWBBNUVNQZ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of At-9283
CAS: 896466-04-9
CID: 135398495
Formula: C19H23N7O2
MW: 381.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight381.4
XLogP30.5
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass381.19132300
Monoisotopic Mass381.19132300
Topological Polar Surface Area111 Ų
Heavy Atom Count28
Formal Charge0
Complexity554
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
A4117-100AT9283

Popular Products