Olaparib

• Target:

  PARP|||Autophagy|||Mitophagy

• Related Pathways:

  Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Autophagy

• Purity:

  >99.99%

• Bioactivity:

  Olaparib (KU0059436) is a small molecule inhibitor of PARP1/PARP2 (IC50=5/1 nM), with weak inhibitory activity against PARP tankyrase-1 (IC50=1.5 ?M), and is selective and orally active. Olaparib exhibits autophagy and mitochondrial autophagy activation activity.

• Smiles:

  C(C=1C=2C(C(=O)NN1)=CC=CC2)C3=CC(C(=O)N4CCN(C(=O)C5CC5)CC4)=C(F)C=C3

• Molecular Formula:

  C24H23FN4O3

• Molecular Weight:

  434.46

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  763113-22-0