Olaparib

• CAS Number :

  763113-22-0

• Target :

  PARP|||Autophagy|||Mitophagy

• Related Pathways :

  Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Autophagy

• Purity :

  >99.99%

• Bioactivity :

  Olaparib (KU0059436) is a small molecule inhibitor of PARP1/PARP2 (IC50=5/1 nM), with weak inhibitory activity against PARP tankyrase-1 (IC50=1.5 ?M), and is selective and orally active. Olaparib exhibits autophagy and mitochondrial autophagy activation activity.

• Smiles :

  C(C=1C=2C(C(=O)NN1)=CC=CC2)C3=CC(C(=O)N4CCN(C(=O)C5CC5)CC4)=C(F)C=C3

• Molecular Formula :

  C24H23FN4O3

• Molecular Weight :

  434.46

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C